CRAZY MOVIE MISTAKES! See the mistakes the producers missed when making Mean Girls. Mean Girls is a 2004 American teen comedy film directed by Mark Waters. The screenplay was written by Tina Fey and is based in part on the non-fiction book Queen Bees and Wannabes by Rosalind Wiseman, which describes how female high school social cliques operate and the effect they can have on girls. The film stars Lindsay Lohan and features a supporting cast of Rachel McAdams, Lacey Chabert, Amanda Seyfried (in her film debut), and Lizzy Caplan.